Is there a link among the pathogenic mechanisms associated with neurodegenerative disease? Multiple pathways have been identified as playing a role in the development and progression of neurodegenerative diseases such as Amyotrophic Lateral Sclerosis (ALS), but it is unclear how they are connected. Our current research investigates the role of the actin cytoskeleton –– […]
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Ross Research
Ross Overview
The Ross Lab investigates fundamental questions of aging. Our primary objectives are directed toward understanding the metabolic consequences and underlying molecular mechanisms of aging and age-related diseases, with a particular focus on brain aging and neurodegenerative diseases, including Alzheimer’s and Parkinson’s diseases. Our work investigates the interconnectedness of several hallmarks of the aging process: mitochondrial […]
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Jaime M. Ross, Ph.D. joined the URI Faculty in October 2019 and is an Assistant Professor of Neuroscience within the George and Anne Ryan Institute for Neuroscience and Biomedical and Pharmaceutical Sciences in the College of Pharmacy. Dr. Ross is a native of Southern Vermont and attended Saint Lawrence University, where she studied Neuroscience and Fine Arts. Dr. […]
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(♯) Corresponding author(†) signifies trainees Select Publications Mitochondrial Dysfunction and Protein Homeostasis in Aging: Insights from a Premature-Aging Mouse Model. Ross JM*, Olson L, Coppotelli G*. MDPI, January 2024. Gaspar L*, Bartman S*, Coppotelli G*, Ross J*. Effect of apparatus characteristics on anxiety-like behavior in young adult and old mice of both sexes […]
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Cytoskeleton Keys
New faculty member Claudia Fallini investigates how modulation of the cytoskeletal protein actin could potentially be an ALS therapy.
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A new study on the impact of exercise on cerebral amyloid angiopathy shows long-term physical activity may help reduce neuroinflammation.
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