Looking to spinal motor neurons to investigate the mysteries of ALS
Using his unique in vivo approach, Assistant Professor Marin Manuel investigates electrical activity in the spinal motor neurons in a disease model of amyotrophic lateral sclerosis. Also known as Lou Gehrig’s disease, amyotrophic lateral sclerosis (ALS) is a mysterious and fatal disorder where nerve cells in the brain and spinal cord break down, rapidly progressing […]Continue reading "Looking to spinal motor neurons to investigate the mysteries of ALS"
First-in-kind models will help break new ground in studying Alzheimer’s disease and related disorders
Gene-edited rat models will reflect vascular pathology associated with Alzheimer’s and related disorders.Continue reading "First-in-kind models will help break new ground in studying Alzheimer’s disease and related disorders"
Q&A: Giuseppe Coppotelli, Ph.D.
Giuseppe Coppotelli, Ph.D. investigates how protein homeostasis deregulation and mitochondrial dysfunction in the aging brain could contribute to chronic inflammation and dementias such as Alzheimer’s disease. What drew you to this area of research?Growing up, I was always curious about living organisms. How do plants grow? How do they know to turn their leaves to […]Continue reading "Q&A: Giuseppe Coppotelli, Ph.D."
Ryan Institute Co-Director John Robinson named Thomas M. Ryan Professor of Neuroscience
The URI Foundation & Alumni Engagement (URIFAE) is pleased to announce that George and Anne Ryan Institute for Neuroscience Co-Executive Director John K. Robinson has been named Thomas M. Ryan Professor of Neuroscience.Continue reading "Ryan Institute Co-Director John Robinson named Thomas M. Ryan Professor of Neuroscience"
Q&A with Joseph Schrader, Ph.D.
Joe Schrader, research assistant professor of biomedical and pharmaceutical sciences, uses mass spectroscopy proteomics to investigate biomarkers and disease mechanisms in Alzheimer’s disease and related disorders. He shares his thoughts on research, how being a musician makes him a better scientist, and why he hasn’t missed a day of running in seven years. What drew […]Continue reading "Q&A with Joseph Schrader, Ph.D."
__________________________ 2020 Metabolomics biomarker discovery in cerebrospinal fluid for cerebral amyloid angiopathy. Van den Berg E, Kuiperij HB, Van Nostrand WE*, Peters TMA, Coene KLM, Engelke UFH, De Boer S, Verbeek MM. Alzheimer’s & Dementia, December 2020. Wiley. A recommended “minimum data set” framework for SD-OCT retinal image acquisition and analysis from the Atlas of […]Continue reading "Past Publications"
Q&A with Jaime Ross, Ph.D.
Assistant Professor Jaime Ross investigates fundamental questions of aging. In this Q&A, she shares her thoughts on the questions that drive her research and what she finds most encouraging about the aging process. How did you become interested in studying aging?It happened by accident. I was studying a robust model of premature aging developed at […]Continue reading "Q&A with Jaime Ross, Ph.D."
(♯) Corresponding author(†) signifies trainees Potts E†, Coppotelli G, Ross JM#. (July 2020) Histological-based stainings using free-floating method. Journal of Visualized Experiments. Jove, DOI: 10.3791/61622. Ross JM♯. (2011). Visualization of mitochondrial respiratory function using cytochrome c oxidase / succinate dehydrogenase (COX/SDH) double-labeling histochemistry. Journal of Visualized Experiments, (57): e3266, DOI: 10.3791/3266.PMID: 22143245 PubMed(invited by Editor)Continue reading "Ross Protocols"
Q&AThe Power of CollaborationRyan Institute Co-Directors John Robinson and William Van Nostrand team up on a shared vision for the Institute. William Van Nostrand and John Robinson’s ongoing research collaboration began at Stony Brook University more than 15 years ago, thanks to a chance meeting in a park. In 2017, they moved their research programs […]Continue reading "Copy Co-Directors"