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Manuel News
March 9, 2024The Manuel lab participated in the annual Pawtucket Brain Fair hosted by Brain Waves RI, demonstrating how electromyography (“EMG”) controls a prosthesis. Participants were able to remotely open and close a robotic hand by “thinking” about moving their arm. The annual Brain Fair draws hundreds of kids and adults to learn about […]
Continue reading "Manuel News"Manuel Publications
Publications *Ryan Institute affiliation Reedich EJ,* Genry LT,* Steele PR,* Mena Avila E,* Dowaliby L,* Drobyshevsky A, Manuel M,* Quinlan KA.* Spinal Motoneurons Respond Aberrantly to Serotonin in a Rabbit Model of Cerebral Palsy. J Physiol., 2023. Cavarsan CF,* Steele PR,* Genry LT,* Reedich EJ,* McCane LM,* LaPre KJ,* Puritz AC,* Manuel M,* Katenka N, Quinlan […]
Continue reading "Manuel Publications"Manuel Overview
The Motor Systems Lab focuses on unraveling the intricacies of the motor system and understanding how normal motor function is impacted in pathological conditions. Employing a range of cutting-edge techniques, including in vivo electrophysiology, in vitro electrophysiology, viral approaches, and advanced imaging methods, our research aims to shed light on the underlying mechanisms governing […]
Continue reading "Manuel Overview"$8.5 million in NIH grants support Ryan Institute research to help treat cerebral palsy
Assistant Professor Katharina Quinlan is principal investigator on two new grants that could repurpose existing therapeutics to treat the disorder.
Continue reading "$8.5 million in NIH grants support Ryan Institute research to help treat cerebral palsy"Q&A: Jessica Alber, Ph.D.
Her inspiration, the biggest challenges in her work, and what makes her feel hopeful. Assistant Professor Jessica Alber investigates the potential to use retinal imaging as a screening tool for early-stage Alzheimer’s disease. Performed during a routine eye exam, the screening technique could help provide a low-cost, minimally invasive way to detect Alzheimer’s disease before […]
Continue reading "Q&A: Jessica Alber, Ph.D."Q&A: The risks of brain bleeds in antibody treatments for Alzheimer’s disease
Ryan Institute Co-Executive Director William Van Nostrand answers questions about the potential risk of brain bleeds associated with newly-approved lecanemab and similar treatments. This summer, the FDA granted full approval to lecanemab, an antibody treatment for Alzheimer’s disease. The antibody—a protein that works by clearing amyloid-beta protein “plaques” in the brain, a signature of Alzheimer’s disease—has […]
Continue reading "Q&A: The risks of brain bleeds in antibody treatments for Alzheimer’s disease"Van Nostrand lab is part of $8 million grant for U.S. and European consortium on brain clearance in CAA
William Van Nostrand, co-executive director of the George & Anne Ryan Institute for Neuroscience at the Univeristy of Rhode Island, is part of a team awarded a five-year, $8 million grant from the prestigious Leducq Foundation.
Continue reading "Van Nostrand lab is part of $8 million grant for U.S. and European consortium on brain clearance in CAA"People
Postdoc Graduate Students Undergraduate Students Liviana Donatelli (INP, Psy) Alex Burns (INP) Bhavya Chatragadda (INP, CMB-microbiology) Emilie Gastone (CMB) Past members – Undergrads Tinu Oladele Kofo Adebiyi Elizabeth Murphy
Continue reading "People"New affiliated faculty members join the Ryan Institute
The Ryan Institute was pleased to welcome ten new faculty affiliates in Spring 2023 from the College of Pharmacy, College of Health Sciences, and College of Electrical, Computer, and Biomedical Engineering. Specializing in research areas that complement the institute’s focus on pathogenic mechanisms of neurodegenerative disease, our URI network of affiliated faculty are valuable partners […]
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