Giuseppe Coppotelli, Ph.D. investigates how protein homeostasis deregulation and mitochondrial dysfunction in the aging brain could contribute to chronic inflammation and dementias such as Alzheimer’s disease. What drew you to this area of research?Growing up, I was always curious about living organisms. How do plants grow? How do they know to turn their leaves to […]

Assistant Professor Jaime Ross investigates fundamental questions of aging. In this Q&A, she shares her thoughts on the questions that drive her research and what she finds most encouraging about the aging process. How did you become interested in studying aging?It happened by accident. I was studying a robust model of premature aging developed at […]

    Dr. Bill Van Nostrand is the Herrmann Professor of Neuroscience and Co-Director of the George & Anne Ryan Institute for Neuroscience. He is one of the field’s leading researchers on the pathogenesis of cerebral amyloid angiopathy, cerebral small vessel disease, and Alzheimer’s disease using biochemical, molecular, cellular and animal model approaches. He is […]

  Lab photo, names, contact/hiring(?) info goes on this page

  Recent Publications Impact of Aβ40 and Aβ42 Fibrils on the Transcriptome of Primary Astrocytes and Microglia. Zhu X*, Schrader JM*, Irizarry B, Smith SO, Van Nostrand WE. Biomedicines. November 2022. Impact of non-pharmacological chronic hypertension on a transgenic rat model of cerebral amyloid angiopathy. Stanisavljevic A*, Schrader JM*, Zhu X*, Mattar JM*, Hanks A*, Xu F*, Majchrzak M*, Robinson JK*, […]

  What role do the brain blood vessels play in the development and progression of Alzheimer’s disease and related disorders?  The Van Nostrand lab investigates the pathogenesis of Alzheimer’s disease, cerebral amyloid angiopathy, and cerebral small vessel disease using biochemical, molecular, cellular, and animal model approaches. Their preclinical models of disease have been used widely […]

  Perhaps a page that highlights current research projects? 

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