A new grant supports research by the Van Nostrand lab to investigate the effects of the ApoE 4 genotype in cerebral amyloid angiopathy, a disorder that commonly occurs with Alzheimer’s disease.
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Ryan Institute expert discusses new Alzheimer’s disease research showing that changes in the brain also can be seen in the eyes
Assistant Professor Jess Alber answers questions about new research that supports her own work toward screening for Alzheimer’s disease during routine eye exams.
Continue reading "Ryan Institute expert discusses new Alzheimer’s disease research showing that changes in the brain also can be seen in the eyes"Looking to spinal motor neurons to investigate the mysteries of ALS
Using his unique in vivo approach, Assistant Professor Marin Manuel investigates electrical activity in the spinal motor neurons in a disease model of amyotrophic lateral sclerosis. Also known as Lou Gehrig’s disease, amyotrophic lateral sclerosis (ALS) is a mysterious and fatal disorder where nerve cells in the brain and spinal cord break down, rapidly progressing […]
Continue reading "Looking to spinal motor neurons to investigate the mysteries of ALS"First-in-kind models will help break new ground in studying Alzheimer’s disease and related disorders
Gene-edited rat models will reflect vascular pathology associated with Alzheimer’s and related disorders.
Continue reading "First-in-kind models will help break new ground in studying Alzheimer’s disease and related disorders"Ryan Institute researchers are part of breakthrough studies on “mature” neurons, epigenetics in aging
Three Ryan Institute faculty are co-authors on breakthrough studies at Northwestern University and Harvard Medical School.
Continue reading "Ryan Institute researchers are part of breakthrough studies on “mature” neurons, epigenetics in aging"Q&A: Giuseppe Coppotelli, Ph.D.
Giuseppe Coppotelli, Ph.D. investigates how protein homeostasis deregulation and mitochondrial dysfunction in the aging brain could contribute to chronic inflammation and dementias such as Alzheimer’s disease. What drew you to this area of research?Growing up, I was always curious about living organisms. How do plants grow? How do they know to turn their leaves to […]
Continue reading "Q&A: Giuseppe Coppotelli, Ph.D."Q&A with Jaime Ross, Ph.D.
Assistant Professor Jaime Ross investigates fundamental questions of aging. In this Q&A, she shares her thoughts on the questions that drive her research and what she finds most encouraging about the aging process. How did you become interested in studying aging?It happened by accident. I was studying a robust model of premature aging developed at […]
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(♯) Corresponding author(†) signifies trainees Adelöf J, Ross JM, Zetterberg M, Hernebring M. (2021). Survival-Span Method: How to Qualitatively Estimate Lifespan to Improve the Study of Aging, and not Disease, in Aging Studies. Frontiers in Aging, Dec 2021. Potts E†, Coppotelli G, Ross JM#. (July 2020) Histological-based stainings using free-floating method. Journal of Visualized Experiments. […]
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In the News Additional Lab Highlights August 2024 Drs. Ross and Coppotelli received a two-year, $433,125 NIH grant to characterize a new mouse model of mitochondrial dysfunction. The model will allow researchers to isolate mtDNA mutations within single tissues to more accurately understand the impacts on different health and disease states. June 2024 RI-INBRE […]
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Loading… Sydney Bartman Interdisciplinary Neuroscience Program, Ph.D. candidate sydney0318@my.uri.edu Emily Potts Interdisciplinary Neuroscience Program, Ph.D. candidate emily_potts@my.uri.edu Lila Berle Undergraduate Researcher lila_berle@my.uri.edu Panorea Tirja Undergraduate Researcher panoreat6@my.uri.edu Leah Harmon SURF Fellow 2020 University of Notre Dame
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