Using his unique in vivo approach, Assistant Professor Marin Manuel investigates electrical activity in the spinal motor neurons in a disease model of amyotrophic lateral sclerosis. Also known as Lou Gehrig’s disease, amyotrophic lateral sclerosis (ALS) is a mysterious and fatal disorder where nerve cells in the brain and spinal cord break down, rapidly progressing […]
Continue reading "Looking to spinal motor neurons to investigate the mysteries of ALS"Author: maranhas
First-in-kind models will help break new ground in studying Alzheimer’s disease and related disorders
Gene-edited rat models will reflect vascular pathology associated with Alzheimer’s and related disorders.
Continue reading "First-in-kind models will help break new ground in studying Alzheimer’s disease and related disorders"Ryan Institute researchers are part of breakthrough studies on “mature” neurons, epigenetics in aging
Three Ryan Institute faculty are co-authors on breakthrough studies at Northwestern University and Harvard Medical School.
Continue reading "Ryan Institute researchers are part of breakthrough studies on “mature” neurons, epigenetics in aging"Q&A: Giuseppe Coppotelli, Ph.D.
Giuseppe Coppotelli, Ph.D. investigates how protein homeostasis deregulation and mitochondrial dysfunction in the aging brain could contribute to chronic inflammation and dementias such as Alzheimer’s disease. What drew you to this area of research?Growing up, I was always curious about living organisms. How do plants grow? How do they know to turn their leaves to […]
Continue reading "Q&A: Giuseppe Coppotelli, Ph.D."Ryan Institute Co-Director John Robinson named Thomas M. Ryan Professor of Neuroscience
The URI Foundation & Alumni Engagement (URIFAE) is pleased to announce that George and Anne Ryan Institute for Neuroscience Co-Executive Director John K. Robinson has been named Thomas M. Ryan Professor of Neuroscience.
Continue reading "Ryan Institute Co-Director John Robinson named Thomas M. Ryan Professor of Neuroscience"Assistant Professor Jessica Alber receives $10.3 million grant for research on retinal scanning
The five-year, $10.3 million grant from the National Institutes of Health will support Dr. Alber’s research on using retinal imaging to screen for early changes associated with Alzheimer’s disease.
Continue reading "Assistant Professor Jessica Alber receives $10.3 million grant for research on retinal scanning"Leading researchers take on next chapter as Ryan Institute Co-Executive Directors
With a shared vision for the institute’s future, William Van Nostrand and John Robinson bring a complementary approach to leadership that reflects the successful partnership they have honed during decades of research collaboration.
Continue reading "Leading researchers take on next chapter as Ryan Institute Co-Executive Directors"Q&A with Joseph Schrader, Ph.D.
Joe Schrader, research assistant professor of biomedical and pharmaceutical sciences, uses mass spectroscopy proteomics to investigate biomarkers and disease mechanisms in Alzheimer’s disease and related disorders. He shares his thoughts on research, how being a musician makes him a better scientist, and why he hasn’t missed a day of running in seven years. What drew […]
Continue reading "Q&A with Joseph Schrader, Ph.D."URI-affiliated biotech raises $12 million for Alzheimer’s research
MindImmune co-founders Frank Menniti and Robert Nelson are affiliated faculty at the Ryan Institute. This funding advances their work on an antibody treatment that targets peripheral immune cells found to play a role in driving Alzheimer’s disease.
Continue reading "URI-affiliated biotech raises $12 million for Alzheimer’s research"Dysfunction in brain’s clearance systems may contribute to CAA
A new study published in Nature Aging and conducted by William Van Nostrand in collaboration with Yale School of Medicine and Stony Brook University shows that trouble with the brain’s clearance systems may contribute to cerebral amyloid angiopathy (CAA).
Continue reading "Dysfunction in brain’s clearance systems may contribute to CAA"