Ryan Institute Co-Executive Director William Van Nostrand answers questions about the potential risk of brain bleeds associated with newly-approved lecanemab and similar treatments. This summer, the FDA granted full approval to lecanemab, an antibody treatment for Alzheimer’s disease. The antibody—a protein that works by clearing amyloid-beta protein “plaques” in the brain, a signature of Alzheimer’s disease—has […]
Continue reading "Q&A: The risks of brain bleeds in antibody treatments for Alzheimer’s disease"Author: maranhas
Van Nostrand lab is part of $8 million grant for U.S. and European consortium on brain clearance in CAA
William Van Nostrand, co-executive director of the George & Anne Ryan Institute for Neuroscience at the Univeristy of Rhode Island, is part of a team awarded a five-year, $8 million grant from the prestigious Leducq Foundation.
Continue reading "Van Nostrand lab is part of $8 million grant for U.S. and European consortium on brain clearance in CAA"People
Postdoc Graduate Students Undergraduate Students Liviana Donatelli (INP, Psy) Alex Burns (INP) Bhavya Chatragadda (INP, CMB-microbiology) Emilie Gastone (CMB) Past members – Undergrads Tinu Oladele Kofo Adebiyi Elizabeth Murphy
Continue reading "People"New affiliated faculty members join the Ryan Institute
The Ryan Institute was pleased to welcome ten new faculty affiliates in Spring 2023 from the College of Pharmacy, College of Health Sciences, and College of Electrical, Computer, and Biomedical Engineering. Specializing in research areas that complement the institute’s focus on pathogenic mechanisms of neurodegenerative disease, our URI network of affiliated faculty are valuable partners […]
Continue reading "New affiliated faculty members join the Ryan Institute"Graduate Students Receive Top Awards at Neuron 2023
April 27, 2023 URI neuroscience graduate students Emily Potts and Michelle Gregoire received awards at the Neuron 2023 research conference at Quinnipiac University’s Frank H. Netter MD School of Medicine on Sunday, April 23. The event was co-sponsored by the University of Connecticut. Students from the labs of Ryan Institute assistant professors Claudia Fallini and […]
Continue reading "Graduate Students Receive Top Awards at Neuron 2023"New grant from Cure Alzheimer’s Fund supports research into the link between ApoE4 and CAA
A new grant supports research by the Van Nostrand lab to investigate the effects of the ApoE 4 genotype in cerebral amyloid angiopathy, a disorder that commonly occurs with Alzheimer’s disease.
Continue reading "New grant from Cure Alzheimer’s Fund supports research into the link between ApoE4 and CAA"Ryan Institute expert discusses new Alzheimer’s disease research showing that changes in the brain also can be seen in the eyes
Assistant Professor Jess Alber answers questions about new research that supports her own work toward screening for Alzheimer’s disease during routine eye exams.
Continue reading "Ryan Institute expert discusses new Alzheimer’s disease research showing that changes in the brain also can be seen in the eyes"Looking to spinal motor neurons to investigate the mysteries of ALS
Using his unique in vivo approach, Assistant Professor Marin Manuel investigates electrical activity in the spinal motor neurons in a disease model of amyotrophic lateral sclerosis. Also known as Lou Gehrig’s disease, amyotrophic lateral sclerosis (ALS) is a mysterious and fatal disorder where nerve cells in the brain and spinal cord break down, rapidly progressing […]
Continue reading "Looking to spinal motor neurons to investigate the mysteries of ALS"First-in-kind models will help break new ground in studying Alzheimer’s disease and related disorders
Gene-edited rat models will reflect vascular pathology associated with Alzheimer’s and related disorders.
Continue reading "First-in-kind models will help break new ground in studying Alzheimer’s disease and related disorders"