The Ross Lab investigates fundamental questions of aging. Our primary objectives are directed toward understanding the metabolic consequences and underlying molecular mechanisms of aging and age-related diseases, with a particular focus on brain aging and neurodegenerative diseases, including Alzheimer’s and Parkinson’s diseases. Our work investigates the interconnectedness of several hallmarks of the aging process: mitochondrial […]
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Ross Biography
Jaime M. Ross, Ph.D. joined the URI Faculty in October 2019 and is an Assistant Professor of Neuroscience within the George and Anne Ryan Institute for Neuroscience and Biomedical and Pharmaceutical Sciences in the College of Pharmacy. Dr. Ross is a native of Southern Vermont and attended Saint Lawrence University, where she studied Neuroscience and Fine Arts. Dr. […]
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(♯) Corresponding author(†) signifies trainees Select Publications Mitochondrial Dysfunction: A Key Player in Brain Diseases. Bartman S*, Coppotelli G*, Ross JM*. Current Issues in Molecular Biology, February 2024. Mitochondrial Dysfunction and Protein Homeostasis in Aging: Insights from a Premature-Aging Mouse Model. Ross JM*, Olson L, Coppotelli G*. MDPI, January 2024. Gaspar L*, Bartman S*, Coppotelli […]
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The Ryan Institute is included in a spotlight on shifting trends in Alzheimer’s research in the latest issue of Science.
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New faculty member Claudia Fallini investigates how modulation of the cytoskeletal protein actin could potentially be an ALS therapy.
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Tom and Cathy Ryan give $24 million to support Ryan Institute research, as part of historic $35 million gift to URI.
Continue reading "Historic gift benefits neurodegenerative disease research"Van Nostrand Biography
Dr. Bill Van Nostrand is the Herrmann Professor of Neuroscience and Co-Director of the George & Anne Ryan Institute for Neuroscience. He is one of the field’s leading researchers on the pathogenesis of cerebral amyloid angiopathy, cerebral small vessel disease, and Alzheimer’s disease using biochemical, molecular, cellular and animal model approaches. He is […]
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Recent Publications Impact of Aβ40 and Aβ42 Fibrils on the Transcriptome of Primary Astrocytes and Microglia. Zhu X*, Schrader JM*, Irizarry B, Smith SO, Van Nostrand WE. Biomedicines. November 2022. Impact of non-pharmacological chronic hypertension on a transgenic rat model of cerebral amyloid angiopathy. Stanisavljevic A*, Schrader JM*, Zhu X*, Mattar JM*, Hanks A*, Xu F*, Majchrzak M*, Robinson JK*, […]
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