(♯) Corresponding author(†) signifies trainees Select Publications Mitochondrial Dysfunction: A Key Player in Brain Diseases. Bartman S*, Coppotelli G*, Ross JM*. Current Issues in Molecular Biology, February 2024. Mitochondrial Dysfunction and Protein Homeostasis in Aging: Insights from a Premature-Aging Mouse Model. Ross JM*, Olson L, Coppotelli G*. MDPI, January 2024. Gaspar L*, Bartman S*, Coppotelli […]
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Spotlight in Science
The Ryan Institute is included in a spotlight on shifting trends in Alzheimer’s research in the latest issue of Science.
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New faculty member Claudia Fallini investigates how modulation of the cytoskeletal protein actin could potentially be an ALS therapy.
Continue reading "Cytoskeleton Keys"Historic gift benefits neurodegenerative disease research
Tom and Cathy Ryan give $24 million to support Ryan Institute research, as part of historic $35 million gift to URI.
Continue reading "Historic gift benefits neurodegenerative disease research"Van Nostrand Biography
Dr. Bill Van Nostrand is the Herrmann Professor of Neuroscience and Co-Director of the George & Anne Ryan Institute for Neuroscience. He is one of the field’s leading researchers on the pathogenesis of cerebral amyloid angiopathy, cerebral small vessel disease, and Alzheimer’s disease using biochemical, molecular, cellular and animal model approaches. He is […]
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Lab photo, names, contact/hiring(?) info goes on this page
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Recent Publications Impact of Aβ40 and Aβ42 Fibrils on the Transcriptome of Primary Astrocytes and Microglia. Zhu X*, Schrader JM*, Irizarry B, Smith SO, Van Nostrand WE. Biomedicines. November 2022. Impact of non-pharmacological chronic hypertension on a transgenic rat model of cerebral amyloid angiopathy. Stanisavljevic A*, Schrader JM*, Zhu X*, Mattar JM*, Hanks A*, Xu F*, Majchrzak M*, Robinson JK*, […]
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What role do the brain blood vessels play in the development and progression of Alzheimer’s disease and related disorders? The Van Nostrand lab investigates the pathogenesis of Alzheimer’s disease, cerebral amyloid angiopathy, and cerebral small vessel disease using biochemical, molecular, cellular, and animal model approaches. Their preclinical models of disease have been used widely […]
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Perhaps a page that highlights current research projects?
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What happens to the motor neurons in diseases like amyotrophic lateral sclerosis (ALS), spinal muscular atrophy (SMA), and cerebral palsy? The Quinlan lab is dedicated to investigating how spinal neurons change and deteriorate in neurodegenerative diseases or after injuries where movement is critically impaired or lost. The lab’s research focuses on identifying the early morphological […]
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