Q&AThe Power of CollaborationRyan Institute Co-Directors John Robinson and William Van Nostrand team up on a shared vision for the Institute. William Van Nostrand and John Robinson’s ongoing research collaboration began at Stony Brook University more than 15 years ago, thanks to a chance meeting in a park. In 2017, they moved their research programs […]
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Co-Directors
Q&AThe Power of CollaborationRyan Institute Co-Directors John Robinson and William Van Nostrand team up on a shared passion for the future of the Ryan Institute. William Van Nostrand and John Robinson’s ongoing research collaboration began at Stony Brook University more than 15 years ago, thanks to a chance meeting in a park. In 2017, they […]
Continue reading "Co-Directors"Ross News
August 2024 The Ross lab received a two-year, $433,125 NIH grant to characterize a new mouse model of mitochondrial dysfunction. The model will allow researchers to isolate mtDNA mutations within single tissues to more accurately understand the impacts on different health and disease states. June 2024 RI-INBRE highlighted the Ross lab’s work on microplastics […]
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Loading… Sydney Bartman Interdisciplinary Neuroscience Program, Ph.D. candidate sydney0318@my.uri.edu Emily Potts Interdisciplinary Neuroscience Program, Ph.D. candidate emily_potts@my.uri.edu Lila Berle Undergraduate Researcher lila_berle@my.uri.edu Panorea Tirja Undergraduate Researcher panoreat6@my.uri.edu Leah Harmon SURF Fellow 2020 University of Notre Dame
Continue reading "Staff – practice"URI Brain Fair
2020 URI Brain Fair: Saturday, March 21 | 10 a.m. – 2 p.m. Save the date for the fourth annual URI Brain Fair! Details here. Highlights from the 2019 URI Brain Fair On March 16, 2019, our third annual URI Brain Fair drew hundreds of kids and adults to learn about the brain and some […]
Continue reading "URI Brain Fair"Fallini News
September 2023. The Fallini lab received a $413,729 NIH grant to study the link between stroke and Alzheimer’s disease. April 2023. Students in the Fallini lab participated in the Neuron 2023 Conference at Quinnipiac University, taking home top awards.
Continue reading "Fallini News"Fallini Bio + Contact
Dr. Fallini received her Ph.D. from the Università degli Studi di Milano (Italy) in 2009, where she gained interest in the basic cellular and molecular mechanisms leading to neurodegeneration, with a particular focus on the role of mRNA regulation in the maintenance and function of motor neurons. After she graduated, she moved […]
Continue reading "Fallini Bio + Contact"Fallini Publications
ALS-associated KIF5A mutations abolish autoinhibition resulting in a toxic gain of function. Baron DM et al (incl Fallini C.*). Cell Reports. April 2022. Traffic jam at the nuclear pore: All roads lead to nucleocytoplasmic transport defects in ALS/FTD. Fallini C, Khalil B, Smith CL, Rossol W. Neurobiology of Disease, July 2020. ScienceDirect. Modulation […]
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The overarching goal of the Fallini Lab is to dissect the molecular and cellular changes that occur in postmitotic neurons during aging and in pathological conditions, such as Amyotrophic Lateral Sclerosis, Frontotemporal Dementia (ALS/FTD) and Alzheimer’s disease. Our current research is focused on investigating the crosstalk between the actin cytoskeleton, a regulator of cell […]
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Is there a link among the pathogenic mechanisms associated with neurodegenerative disease? Multiple pathways have been identified as playing a role in the development and progression of neurodegenerative diseases such as Amyotrophic Lateral Sclerosis (ALS), but it is unclear how they are connected. Our current research investigates the role of the actin cytoskeleton –– […]
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