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Manuel News
March 9, 2024The Manuel lab participated in the annual Pawtucket Brain Fair hosted by Brain Waves RI, demonstrating how electromyography (“EMG”) controls a prosthesis. Participants were able to remotely open and close a robotic hand by “thinking” about moving their arm. The annual Brain Fair draws hundreds of kids and adults to learn about […]
Continue reading "Manuel News"Manuel Publications
Publications *Ryan Institute affiliation Reedich EJ,* Genry LT,* Steele PR,* Mena Avila E,* Dowaliby L,* Drobyshevsky A, Manuel M,* Quinlan KA.* Spinal Motoneurons Respond Aberrantly to Serotonin in a Rabbit Model of Cerebral Palsy. J Physiol., 2023. Cavarsan CF,* Steele PR,* Genry LT,* Reedich EJ,* McCane LM,* LaPre KJ,* Puritz AC,* Manuel M,* Katenka N, Quinlan […]
Continue reading "Manuel Publications"Manuel Overview
The Motor Systems Lab focuses on unraveling the intricacies of the motor system and understanding how normal motor function is impacted in pathological conditions. Employing a range of cutting-edge techniques, including in vivo electrophysiology, in vitro electrophysiology, viral approaches, and advanced imaging methods, our research aims to shed light on the underlying mechanisms governing […]
Continue reading "Manuel Overview"$413,729 NIH grant helps to study the link between stroke and Alzheimer’s disease
Assistant Professor Claudia Fallini hopes the research will lead to new Alzheimer’s disease insights and improved stroke outcomes.
Continue reading "$413,729 NIH grant helps to study the link between stroke and Alzheimer’s disease"Van Nostrand lab collaborates with Eli Lilly to investigate brain bleed risk in Alzheimer’s disease treatments
The project will help shed light on whether there may be a way to reduce or eliminate the risk.
Continue reading "Van Nostrand lab collaborates with Eli Lilly to investigate brain bleed risk in Alzheimer’s disease treatments"$8.5 million in NIH grants support Ryan Institute research to help treat cerebral palsy
Assistant Professor Katharina Quinlan is principal investigator on two new grants that could repurpose existing therapeutics to treat the disorder.
Continue reading "$8.5 million in NIH grants support Ryan Institute research to help treat cerebral palsy"Q&A: Jessica Alber, Ph.D.
Her inspiration, the biggest challenges in her work, and what makes her feel hopeful. Assistant Professor Jessica Alber investigates the potential to use retinal imaging as a screening tool for early-stage Alzheimer’s disease. Performed during a routine eye exam, the screening technique could help provide a low-cost, minimally invasive way to detect Alzheimer’s disease before […]
Continue reading "Q&A: Jessica Alber, Ph.D."A new study investigates the impact of microplastics in the brain
Assistant Professor Jaime Ross and her lab report surprising findings on the impact of short-term microplastics exposure through drinking water.
Continue reading "A new study investigates the impact of microplastics in the brain"Q&A: The risks of brain bleeds in antibody treatments for Alzheimer’s disease
Ryan Institute Co-Executive Director William Van Nostrand answers questions about the potential risk of brain bleeds associated with newly-approved lecanemab and similar treatments. This summer, the FDA granted full approval to lecanemab, an antibody treatment for Alzheimer’s disease. The antibody—a protein that works by clearing amyloid-beta protein “plaques” in the brain, a signature of Alzheimer’s disease—has […]
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