Dr. Bill Van Nostrand is the Herrmann Professor of Neuroscience and Co-Director of the George & Anne Ryan Institute for Neuroscience. He is one of the field’s leading researchers on the pathogenesis of cerebral amyloid angiopathy, cerebral small vessel disease, and Alzheimer’s disease using biochemical, molecular, cellular and animal model approaches. He is […]
Continue reading "Van Nostrand Biography"Category: Uncategorized
Van Nostrand Lab Staff
Lab photo, names, contact/hiring(?) info goes on this page
Continue reading "Van Nostrand Lab Staff"Van Nostrand Publications
Recent Publications Impact of Aβ40 and Aβ42 Fibrils on the Transcriptome of Primary Astrocytes and Microglia. Zhu X*, Schrader JM*, Irizarry B, Smith SO, Van Nostrand WE. Biomedicines. November 2022. Impact of non-pharmacological chronic hypertension on a transgenic rat model of cerebral amyloid angiopathy. Stanisavljevic A*, Schrader JM*, Zhu X*, Mattar JM*, Hanks A*, Xu F*, Majchrzak M*, Robinson JK*, […]
Continue reading "Van Nostrand Publications"Van Nostrand Overview
What role do the brain blood vessels play in the development and progression of Alzheimer’s disease and related disorders? The Van Nostrand lab investigates the pathogenesis of Alzheimer’s disease, cerebral amyloid angiopathy, and cerebral small vessel disease using biochemical, molecular, cellular, and animal model approaches. Their preclinical models of disease have been used widely […]
Continue reading "Van Nostrand Overview"Van Nostrand Research
Perhaps a page that highlights current research projects?
Continue reading "Van Nostrand Research"Quinlan Overview
What happens to the motor neurons in diseases like amyotrophic lateral sclerosis (ALS), spinal muscular atrophy (SMA), and cerebral palsy? The Quinlan lab is dedicated to investigating how spinal neurons change and deteriorate in neurodegenerative diseases or after injuries where movement is critically impaired or lost. The lab’s research focuses on identifying the early morphological […]
Continue reading "Quinlan Overview"Quinlan Biography
Katharina Quinlan investigates early mechanisms of motor dysfunction in disorders such as amyotrophic lateral sclerosis (ALS), spinal muscular atrophy, and cerebral palsy. Over the past decade, her research has been at the forefront of discovering compensatory changes in the neural network that precede the loss of motor control associated with late stages of these […]
Continue reading "Quinlan Biography"Quinlan Lab Staff
Biographies Biographies Lisa Dowaliby (Lab Manager/Certified Veterinary Technician) has been in the veterinary medical field for more than 30 years. She has worked in general practice and emergency veterinary medicine, specializing in exotics, with a background in management and teaching. Dowaliby oversees Institutional Animal Care and Use Committee (IACUC) protocols and compliance for the […]
Continue reading "Quinlan Lab Staff"Quinlan Publications
* Denotes Quinlan lab affiliation Selected Publications Facilitation of sensory transmission to motoneurons during cortical or sensory evoked primary afferent depolarization (PAD) in humans.Metz K et al (incl. Quinlan KA*). Journal of Physiology. March 2023. Inhibitory interneurons show early dysfunction in a SOD1 mouse model of amyotrophic lateral sclerosis. Cavarsan CF*, Steele PR*, Genry LT*, […]
Continue reading "Quinlan Publications"Quinlan research
Cerebral palsy Affecting 1 in 400 births, cerebral palsy (CP) is a movement disorder that permanently impairs motor control, caused by injuries during prenatal development. Much of the existing research on CP is focused on effects of brain injury; the Quinlan lab investigates changes to the spinal cord that contribute to motor […]
Continue reading "Quinlan research"