NEW FACULTY Cytoskeleton Keys Claudia Fallini, Ph.D. is investigating a critical gateway that may provide clues into the causes of ALS. In the mystery of amyotrophic lateral sclerosis (ALS), Claudia Fallini is looking to connect some dots. In recent years, researchers have found potential clues to the puzzling and fatal disease, which causes the progressive […]

    Dr. Bill Van Nostrand is the Herrmann Professor of Neuroscience and Co-Director of the George & Anne Ryan Institute for Neuroscience. He is one of the field’s leading researchers on the pathogenesis of cerebral amyloid angiopathy, cerebral small vessel disease, and Alzheimer’s disease using biochemical, molecular, cellular and animal model approaches. He is […]

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  Recent Publications Impact of Aβ40 and Aβ42 Fibrils on the Transcriptome of Primary Astrocytes and Microglia. Zhu X*, Schrader JM*, Irizarry B, Smith SO, Van Nostrand WE. Biomedicines. November 2022. Impact of non-pharmacological chronic hypertension on a transgenic rat model of cerebral amyloid angiopathy. Stanisavljevic A*, Schrader JM*, Zhu X*, Mattar JM*, Hanks A*, Xu F*, Majchrzak M*, Robinson JK*, […]

  What role do the brain blood vessels play in the development and progression of Alzheimer’s disease and related disorders?  The Van Nostrand lab investigates the pathogenesis of Alzheimer’s disease, cerebral amyloid angiopathy, and cerebral small vessel disease using biochemical, molecular, cellular, and animal model approaches. Their preclinical models of disease have been used widely […]