Early disruption of the CREB pathway drives dendritic morphological alterations in FTD/ALS cortical neurons. Gregoire MJ, Sirtori R, Donatelli L, Potts EM, Collins A, Zamor D, Katenka N, Fallini C. Journal of the Proceedings of the National Academy of Sciences, December 2024
LINC complex alterations are a key feature of sporadic and familial ALS/FTD. Sirtori R, Gregoire MJ, Potts EM, Collins A, Donatelli L, Fallini C. Acta Neuropathologica Communications, April 2024.
ALS-associated KIF5A mutations abolish autoinhibition resulting in a toxic gain of function. Baron DM et al (incl Fallini C.*). Cell Reports. April 2022.
Traffic jam at the nuclear pore: All roads lead to nucleocytoplasmic transport defects in ALS/FTD. Fallini C, Khalil B, Smith CL, Rossol W. Neurobiology of Disease, July 2020.
Modulation of actin polymerization affects nucleocytoplasmic transport in multiple forms of amyotrophic lateral sclerosis. Giampetruzzi A, Danielson EW, Gumina V, Jeon M, Boopathy S, Brown RH, Ratti A, Landers JE, Fallini C. Modulation of actin polymerization affects nucleocytoplasmic transport in the multiple forms of amyotrophic lateral sclerosis. Nature Communications, 2019; 10:3827.