Artificial extracellular matrix scaffolds of mobile molecules enhance maturation of human stem cell-derived neurons. Zaida A et al (including Quinlan KA*). Cell Stem Cell. January 2023.
Impact of Aβ40 and Aβ42 Fibrils on the Transcriptome of Primary Astrocytes and Microglia. Zhu X*, Schrader JM*, Irizarry B, Smith SO, Van Nostrand WE. Biomedicines. November 2022.
Enhanced nociceptive behavior and expansion of associated primary afferents in a rabbit model of cerebral palsy. Reedich EJ*, Genry LT*, Singer MA, Cavarsan CF*, Avila EM*, Boudreau DM*, Michael C Brennan MC*, Garrett AM*, Dowaliby L*, Detloff MR, Quinlan KA*. Journal of Neuroscience Research. July 2022.
Sex differences in metabolic indices and chronic neuroinflammation in response to prolonged high-fat diet in ApoE4 knock-in mice. Mattar JM, Majchrzak M*, Iannucci J, Bartman S, Robinson JK*, Grammas P. International Journal of Molecular Science, Special Issue on Pathogenesis of Alzheimer’s disease. April 2022.
ALS-associated KIF5A mutations abolish autoinhibition resulting in a toxic gain of function. Baron DM et al (incl Fallini C.*). Cell Reports. April 2022.
Impact of non-pharmacological chronic hypertension on a transgenic rat model of cerebral amyloid angiopathy. Stanisavljevic A*, Schrader JM*, Zhu X*, Mattar JM*, Hanks A*, Xu F*, Majchrzak M*, Robinson JK*, Van Nostrand WE*. Frontiers in Neuroscience, March 2022.
Elevated expression of urokinase plasminogen activator in rodent models and patients with cerebral amyloid angiopathy. Vervuurt M, Zhu X, Schrader J, de Kort A, Marques TM, Kersten I, Kuiperji HB, Klijn CJM, Van Nostrand WE*, and Verbeek MM. Neuropathology and Applied Neurobiology, March 2022.
rTg-D: A novel transgenic rat model of cerebral amyloid angiopathy type-2. Davis J, Xu F, Zhu X, and Van Nostrand WE. Cerebral Circulation – Cognition and Behavior, March 2022.
Cerebral amyloid angiopathy is associated with glymphatic transport reduction and time-delayed solute drainage along the neck arteries. Chen X, Liu X, Koundal S, Elkin R, Zhu X, Monte B, Xu F, Dai F, Pedram M, Lee H, Kipnis J, Tannenbaum A, Van Nostrand WE, Benveniste H. Nature Aging, February 2022.
Mitochondrial and metabolic dysfunction in ageing and age-related diseases. Amorim JA, Coppotelli G*, Rolo AP, Palmeira CM, Ross JM*, Sinclair DA. Nature Reviews Endocrinology, February 2022.
A Neuropsychological Perspective on Defining Cognitive Impairment in the Clinical Study of Alzheimer’s Disease: Towards a More Continuous Approach. Jutten R, Thompson L, Sikkes SAM, Maruff P, Molinuevo JL, Zetterberg H, Alber J*, Faust D, Gauthier S, Gold M, Harrison J, Lee AKW, Snyder PJ. Journal of Alzheimer’s Disease, January 2022.
Survival-span method: How to qualitatively estimate lifespan to improve the study of aging, and not disease, in aging studies. Adelöf J, Ross JM*, Zetterberg M, Hernebring M. Frontiers in Aging. December 2021.
Emergent white matter degeneration in the rTg-DI rat model of cerebral amyloid angiopathy exhibits unique proteomic changes. Schrader JM*, Xu F*, Lee H, Barlock B, Benveniste H, Van Nostrand WE*. American Journal of Pathology, December 2021.
Normal cerebrospinal fluid concentrations of PDGFRβ in patients with cerebral amyloid angiopathy and Alzheimer’s disease. De Kort AM, Kuiperij HB, Kersten I, Versleijen AAM, Schreuder FHBM, Van Nostrand WE*, Greenberg SM, Klijn CJM, Claassen JAHR, Verbeek MM. Alzheimer’s & Dementia, December 2021.
Human cerebral vascular amyloid contains both antiparallel and parallel in-register Aβ40 fibrils. Irizarry BA, Davis J*, Zhu X*, Boon BDC, Rozemuller AJM, Van Nostrand WE*, Smith SO. Journal of Biological Chemistry, November 2021.
Distinct brain regional proteome changes in the rTg-DI rat model of cerebral amyloid angiopathy. Schrader JM*, Xu F*, Van Nostrand WE*. Journal of Neurochemistry, October 2021.
Novel TUBA4A variant associated with familial frontotemporal dementia. Mol MO, Wong TH, Melhem S, Basu S, Viscusi R, Galjart N, Rozemuller AJM, Fallini C*, et al. Neurology: Genetics, June 2021.
Compounds from mucuna pruriens seeds and their neuroprotective effects. Johnson SL*, Lu Y, Ma H, Seeram NP* and Yuan T. Chemistry of Natural Compounds, May 2021.
Novel TUBA4A Variant Associated With Familial Frontotemporal Dementia. Mol MO et al. (incl Fallini C*). Neurology Genetics, May 2021.
Diffuse white matter loss in a transgenic rat model of cerebral amyloid angiopathy. Lee H, Xu F*, Liu X, Koundal S, Zhu X*, Davis J*, Yanez D, Schrader J*, Stanisavljevic A*, Rothman DL, Wardlaw J, Van Nostrand WE*, Benveniste H. Journal of Cerebral Blood Flow and Metabolism, May 2021.
Isoform-specific effects of Apolipoprotein E on markers of inflammation and toxicity in brain glia and neuronal cells in vitro. Iannucci J*, Sen A*, and Grammas P*. Current Issues in Molecular Biology, May 2021.
The relationship between cerebral and retinal microbleeds in cerebral amyloid angiopathy (CAA): a pilot study. Alber J*, Arthur E, Goldfarb D, Drake J, Boxerman JL, Silver B, Ott BR, Johnson LN, Snyder P*. Journal of the Neurological Sciences, April 2021.
Anti-Parallel β-Hairpin Structure in Soluble Aβ Oligomers of Aβ40-Dutch and Aβ40-Iowa. Ziao F, Van Nostrand WE*, Smith SO. International Journal of Molecular Science, January 2021.
*Ryan Institute affiliation