A Molecular Switch for NMDA Receptor Modulation

menniti-Neuron-100x100A new article inĀ Neuron uses crystallography to elucidate how some negative allosteric modulators of the NMDA receptor exert their influence. NMDA receptors are an important class of excitatory neurotransmitter receptors whose dysfunction is linked to numerous disorders. Ryan Research Professor of Neuroscience Frank Menniti is a co-author of the report.